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Petrosino and coworkers gave an oral dose of 30 mg/kg [ 13 C] 4 -PEA-um to healthy male SD rats and reported a rise in plasma levels from 1 to 22 pmoL/mL within 30 min of gavage (Petrosino et al., 2018)

Meanwhile, Zepbound (tirzepatide) serves as a dual GIP/GLP-1 agonist, harnessing two hormones for improved weight loss results

Glucagon-like peptide-1 (GLP-1) receptor analogs are drugs that mimic fullness hormone GLP-1 and have been shown to reduce appetite, slow digestion, help stabilize blood sugar levels and impact metabolism

Advertisement Article continues below this ad But drug safety experts warn that the prevalence of compounded drugs, and the limited testing they undergo, leaves patients at greater risk of harm